Often, symptoms will develop slowly over time as the cortisol or other hormone levels gradually decrease.

People with adrenal insufficiency typically report some or all of the following symptoms:

  • fatigue or overwhelming exhaustion
  • deepening skin pigmentation (looking like the person has a sun tan even when they haven’t been out in the sun) - primary adrenal insufficiency/Addison's disease only
  • dizziness or light-headedness on standing
  • low blood pressure
  • salt cravings - primary adrenal insufficiency/Addison's
  • weight loss
  • poor appetite
  • nausea or vomiting
  • difficulty concentrating (brain fog)
  • muscle weakness with cramps
  • headaches
  • stomach pains

Hyperpigmentation

The pre-diagnosis symptom of increased pigmentation may be difficult to detect in people with dark skin tone. Therefore, it is vital to check the inside of the mouth and gums.

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